Leica DMI6000 microscope for epifluorescence or bright field imaging. The scope is configured with a range of Plan APO objectives (including 63x oil), ASI stage with multi-slide holder, LED light source, PCO Scientific CMOS camera, and Metamorph acquisition software. It has been optimized to collect image z-stacks and tiled images for mapping, and images can be used for subsequent deconvolution/analyses by individual users. For further information, and training, contact Kathleen Wang (email@example.com).
Mouse lines available include models for fragile X syndrome (Fmr1-knockout; on two background strains) and Angelman syndrome (Ube3a mutant), and the BTBR strain which exhibits autistic-like behaviors.